Advances in primary immunodeficiency diseases in Latin America: epidemiology, research, and perspectives
Article first published online: 24 FEB 2012
© 2012 New York Academy of Sciences.
Annals of the New York Academy of Sciences
Volume 1250, The Year in Human and Medical Genetics: Inborn Errors of Immunity III pages 62–72, February 2012
How to Cite
Errante, P. R., Franco, J. L., Espinosa-Rosales, F. J., Sorensen, R. and Condino-Neto, A. (2012), Advances in primary immunodeficiency diseases in Latin America: epidemiology, research, and perspectives. Annals of the New York Academy of Sciences, 1250: 62–72. doi: 10.1111/j.1749-6632.2011.06289.x
- Issue published online: 24 FEB 2012
- Article first published online: 24 FEB 2012
- primary immunodeficiency;
- Latin America;
- immunodeficiency epidemiology;
- PID registry;
- Latin American Society for Immunodeficiencies
Primary immunodeficiencies (PIDs) are genetic disorders of the immune system comprising many different phenotypes. Although previously considered rare, recent advances in their clinical, epidemiological, and molecular definitions are revealing how much we still need to learn about them. For example, geographical and ethnic variations as well as the impact of certain practices influence their frequency and presentation, making it necessary to consider their study in terms of regions. The Latin American Society for Immunodeficiencies was established as an organization dedicated to provide scientific support for basic and clinical research and to develop tools and educational resources to promote awareness in the medical community. Initiatives such as these are positively influencing the way PIDs are tackled in these countries, as shown by recent reports and publications. This paper provides a historical compilation and a current view of the many issues faced by scientists studying these diseases in these countries, highlighting the diverse scientific contributions and offering a promising perspective for the further developments in this field in Latin America.