Systems pharmacology of complex diseases


Ravi Iyengar, Mount Sinai School of Medicine, Pharmacology and Systems Therapeutics and Systems Biology Center, One Gustave L. Levy Place, Box 1215, New York, NY 10029.


Systems pharmacology approaches can be used to identify and predict drug-induced adverse events. Disease-centered networks within the human interactome allow us to predict which drugs may produce a similar pathophysiology. Such predictions can be tested in animal models.