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Genetic modification of chicken germ cells
Version of Record online: 10 OCT 2012
© 2012 New York Academy of Sciences.
Annals of the New York Academy of Sciences
Volume 1271, Nutrition and Physical Activity in Aging, Obesity, and Cancer pages 104–109, October 2012
How to Cite
Park, T. S. and Han, J. Y. (2012), Genetic modification of chicken germ cells. Annals of the New York Academy of Sciences, 1271: 104–109. doi: 10.1111/j.1749-6632.2012.06744.x
- Issue online: 10 OCT 2012
- Version of Record online: 10 OCT 2012
- primordial germ cell;
- germline chimera;
- avian biotechnology
Over the past two decades numerous reports have demonstrated that the genetic modification of poultry genomes has great potential for improving poultry production; moreover, it may be used as a powerful tool for the production of industrial proteins. To date, transgenic techniques have been established for generating transgenic birds that express recombinant human proteins in hen eggs, as well as tissue-specific genes as an animal model. The production of transgenic birds is a promising approach that could have practical applications in agriculture and biopharmacology, in addition to advancing our understanding of avian biology. Finally, germ cell–mediated transgenesis could provide a more efficient strategy for creating gene-targeted insertions and deletions in avian species.