There is no doubt that experiencing each disease, particularly their therapeutic methods, affects different aspects of a person's life. Little information is available about experiencing this disease and transurethral resection of the prostate (TURP) despite the high level of prevalence of benign prostate hyperplasia (BPH). The aim of this study was to explore the experience of TURP. This research was a qualitative, content analysis study. The data was gathered by conducting in-depth interviews using the interview manual. After interviewing, 15 patients who had undergone TURP were selected through purposive sampling. Accordingly, once reaching data saturation, the data was analysed through the conventional content analysis. Four themes emerged after analysing the data. The findings indicated that the TURP surgery for these patients was equal to surrendering to the disease, having no other options but undergoing surgery, sense of release and relief, and concern over future. The findings of this study led to an increase in the body of knowledge currently existing in providing nursing for patients who had undergone TURP. Nurses at urology wards ought to attend to these points and at the same time respond to patients' demands besides offering a full-fledged post-surgery nursing care by executing training of post-surgery, self-care measures. Moreover, they should offer patient-centered care and training so that there would be the possibility for them to keep in touch with all of the patients who have undergone surgery. In addition, it would facilitate the expression of patients' feelings about their concerns after the surgery and their access to nursing care after being discharged.