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Safety and tolerability of a 6-week course of oseltamivir prophylaxis for seasonal influenza in children

Authors


Keith Reisinger, 116 Green Commons Drive, Pittsburgh, PA 15243, USA.
E-mail: ksrppr@aol.com

Abstract

Please cite this paper as: Reisinger et al. Safety and tolerability of a 6-week course of oseltamivir prophylaxis for seasonal influenza in children. Influenza and Other Respiratory Viruses DOI: 10.1111/j.1750-2659.2012.00367.x.

In an open-label study, 49 children aged 1–12 years received oseltamivir (30–75 mg once daily depending on bodyweight) for 6 weeks for influenza prophylaxis. Seventeen participants reported 22 adverse events (AEs); in three participants, AEs were considered probably drug related (nausea or vomiting). No serious AEs were reported. The tolerability profile was similar to pooled safety data from treatment studies (duration of 5 days) in children.

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