FTY720 Rescue Therapy in the Dark Agouti Rat Model of Experimental Autoimmune Encephalomyelitis: Expression of Central Nervous System Genes and Reversal of Blood-Brain-Barrier Damage

  1. Carolyn A. Foster1,†,*,
  2. Diana Mechtcheriakova1,‡,†,
  3. Maria K. Storch2,
  4. Balázs Balatoni1,§,
  5. Laurence M. Howard1,
  6. Frédéric Bornancin1,
  7. Alexander Wlachos1,
  8. Jury Sobanov1,¶,
  9. Anu Kinnunen3,‖,
  10. Thomas Baumruker1

Article first published online: 6 JUN 2008

DOI: 10.1111/j.1750-3639.2008.00182.x

Issue

Brain Pathology

Brain Pathology

Volume 19, Issue 2, pages 254–266, April 2009

Additional Information

How to Cite

Foster, C. A., Mechtcheriakova, D., Storch, M. K., Balatoni, B., Howard, L. M., Bornancin, F., Wlachos, A., Sobanov, J., Kinnunen, A. and Baumruker, T. (2009), FTY720 Rescue Therapy in the Dark Agouti Rat Model of Experimental Autoimmune Encephalomyelitis: Expression of Central Nervous System Genes and Reversal of Blood-Brain-Barrier Damage. Brain Pathology, 19: 254–266. doi: 10.1111/j.1750-3639.2008.00182.x

Author Information

  1. 1

    Novartis Institutes for BioMedical Research, Vienna, Austria.

  2. 2

    Department of Neurology, Medical University of Graz, Graz, Austria.

  3. 3

    Novartis Pharma AG, Klybeckstrasse 141, Basel, Switzerland.

  1. †

    CAF and DM contributed equally to this work.

  2. ‡

    Present addresses: Department of Pathophysiology, Medical University of Vienna, A-1090 Vienna, Austria;

  3. §

    Novartis Hungary Healthcare, P.O. Box 453/80, H-1537 Budapest, Hungary;

  4. Institute of Immunology, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria;

  5. ‖

    Kontiolahti Health Center, 81100 Kontiolahti, Finland.

*Carolyn A. Foster, PhD, Novartis Institutes for BioMedical Research, Brunner Strasse 59, A-1235 Vienna, Austria (E-mail: carolyn.foster@novartis.com)

  • †

    CAF and DM contributed equally to this work.

  • ‡

    Present addresses: Department of Pathophysiology, Medical University of Vienna, A-1090 Vienna, Austria;

  • §

    Novartis Hungary Healthcare, P.O. Box 453/80, H-1537 Budapest, Hungary;

  • Institute of Immunology, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria;

  • ‖

    Kontiolahti Health Center, 81100 Kontiolahti, Finland.

Publication History

  1. Issue published online: 5 MAR 2009
  2. Article first published online: 6 JUN 2008
  3. Received 18 October 2007; revised 6 April 2008; accepted 9 April 2008.

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