Do postvaccinal sarcomas occur in Australian cats ?
Article first published online: 10 MAR 2008
Australian Veterinary Journal
Volume 75, Issue 2, pages 102–106, February 1997
How to Cite
BURTON, G. and MASON, K. (1997), Do postvaccinal sarcomas occur in Australian cats ?. Australian Veterinary Journal, 75: 102–106. doi: 10.1111/j.1751-0813.1997.tb14167.x
- Issue published online: 10 MAR 2008
- Article first published online: 10 MAR 2008
- Accepted for publication 13 December 1996.
SUMMARY: A soft tissue sarcoma occurred in the interscapular area of a cat, 1 to 7 months after vaccination at that site. The vaccine contained inactivated feline panleucopaenia virus combined with modified live feline herpesvirus and calicrvirus. The tumour showed histological features of both fibrosarcoma and malignant fibrous histiocytoma. The tumour was observed to evolve from the site of a presumed postvaccinal granuloma. Local recurrence 6 weeks post excision necessitated more radical resection. Euthanasia was performed 2 years later when pleural effusion developed. The cause of effusion was not determined. There was no palpable evidence of local tumour regrowth at the time of euthanasia. A causal relationship between vaccination and sarcoma formation is considered based on the temporal association between the two events, the anatomical location of the tumour and histopathology consistent with postvaccinal sarcomas reported overseas. Six other vaccine site fibrosarcomas, potentially vaccine associated using the above criteria, are summarised.