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Successful management of histiocytic ulcerative colitis with enrofloxacin in two Boxer dogs
Article first published online: 28 JUN 2008
Australian Veterinary Journal
Volume 82, Issue 1-2, pages 58–61, January 2004
How to Cite
DAVIES, D., O'HARA, A., IRWIN, P. and GUILFORD, W. (2004), Successful management of histiocytic ulcerative colitis with enrofloxacin in two Boxer dogs. Australian Veterinary Journal, 82: 58–61. doi: 10.1111/j.1751-0813.2004.tb14643.x
- Issue published online: 28 JUN 2008
- Article first published online: 28 JUN 2008
- Accepted for publication 7 April 2003
Two Boxer dogs with histologically confirmed histiocytic ulcera-tive colitis were treated with enrofloxacin, one as sole therapy and one in conjunction with prednisolone, after failure of standard therapy. Clinical remission occurred rapidly in both dogs after commencement of enrofloxacin and in one case where repeat colonoscopy was performed the endoscopic appearance of the mucosa was normal within 2 weeks. Histological examination of the colonic mucosa in this dog after 7 months showed resolution of the cellular infiltration characteristic of histiocytic ulcerative colitis. Histological improvement following therapy in Boxer dogs with histiocytic ulcerative colitis has not been reported previously.