PHOTOCHEMISTRY OF PHEOMELANIN: ACTION SPECTRUM FOR SUPEROXIDE PRODUCTION

Authors


  • †Prior to use, tubes were calibrated with a chemical actinometer solution and only tubes giving values within 1% of each other were employed for further studies.

*Author to whom correspondence should be addressed.

Abstract

Abstract— The action spectrum for superoxide production from aerated aqueous solutions of pheomela-nin was determined by utilizing the nitroblue tetrazolium-superoxide dismutase assay for superoxide. Superoxide production was greatest in the UVC regions, but continued well into the visible wavelengths. The marked increase in superoxide production noted in the UVC-UVB regions of the spectrum suggests that superoxide production may be involved in a number of actinic disorders in fair-skinned humans.

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