On leave from Institute of Molecular Biology, Jagiellonian University, Department of Biophysics, Krakow, Poland.
PHOTOSENSITIZATION OF MELANIN: AN ELECTRON SPIN RESONANCE STUDY OF SENSITIZED RADICAL PRODUCTION AND OXYGEN CONSUMPTION
Article first published online: 2 JAN 2008
Photochemistry and Photobiology
Volume 40, Issue 4, pages 453–459, October 1984
How to Cite
Sealy, R. C., Sarna, T., Wanner, E. J. and Reszka, K. (1984), PHOTOSENSITIZATION OF MELANIN: AN ELECTRON SPIN RESONANCE STUDY OF SENSITIZED RADICAL PRODUCTION AND OXYGEN CONSUMPTION. Photochemistry and Photobiology, 40: 453–459. doi: 10.1111/j.1751-1097.1984.tb04617.x
- Issue published online: 2 JAN 2008
- Article first published online: 2 JAN 2008
- (Received 31 January 1984; accepted 16 April 1984)
Abstract Rose Bengal is shown to photosensitize free-radical production and oxygen consumption in solutions of melanin from autooxidation of 3,4-dihydroxyphenylalanine (DOPA). In anaerobic solutions the sensitizer enhances rates of free-radical production by up to a factor of 20. In aerobic solutions, rates of oxygen consumption can be increased by a factor of several hundred. The reactions appear to involve the triplet state of the sensitizer. The effect of the sensitizer in increasing oxygen consumption is quenched by low concentrations of azide and enhanced by D2O, suggesting that a singlet oxygen mechanism is involved.