This invited paper is part of the Series: Applications of Imaging to Biological and Photobiological Systems.
Live Cell Surface Labeling with Fluorescent Ag Nanocluster Conjugates†
Article first published online: 27 AUG 2008
© 2008 The Authors. Journal Compilation. The American Society of Photobiology
Photochemistry and Photobiology
Volume 84, Issue 6, pages 1435–1439, November/December 2008
How to Cite
Yu, J., Choi, S., Richards, C. I., Antoku, Y. and Dickson, R. M. (2008), Live Cell Surface Labeling with Fluorescent Ag Nanocluster Conjugates. Photochemistry and Photobiology, 84: 1435–1439. doi: 10.1111/j.1751-1097.2008.00434.x
- Issue published online: 3 NOV 2008
- Article first published online: 27 AUG 2008
- Received 10 April 2008, accepted 26 June 2008
DNA-encapsulated silver clusters are readily conjugated to proteins and serve as alternatives to organic dyes and semiconductor quantum dots. Stable and bright on the bulk and single molecule levels, Ag nanocluster fluorescence is readily observed when staining live cell surfaces. Being significantly brighter and more photostable than organics and much smaller than quantum dots with a single point of attachment, these nanomaterials offer promising new approaches for bulk and single molecule biolabeling.