This invited paper is part of the Symposium-in-Print: Photosynthesis.
Hydrogen Peroxide-mediated Inactivation of Two Chloroplastic Peroxidases, Ascorbate Peroxidase and 2-Cys Peroxiredoxin†
Article first published online: 7 OCT 2008
© 2008 The Author. Journal Compilation. The American Society of Photobiology
Photochemistry and Photobiology
Volume 84, Issue 6, pages 1404–1409, November/December 2008
How to Cite
Kitajima, S. (2008), Hydrogen Peroxide-mediated Inactivation of Two Chloroplastic Peroxidases, Ascorbate Peroxidase and 2-Cys Peroxiredoxin. Photochemistry and Photobiology, 84: 1404–1409. doi: 10.1111/j.1751-1097.2008.00452.x
- Issue published online: 3 NOV 2008
- Article first published online: 7 OCT 2008
- Received 30 March 2008, accepted 19 August 2008
Reactive oxygen species (ROS), such as the superoxide anion and hydrogen peroxide, are generated by the photosystems because photoexcited electrons are often generated in excess of requirements for CO2 fixation and used for reducing molecular oxygen, even under normal environmental conditions. Moreover, ROS generation is increased in chloroplasts if plants are subjected to stresses, such as drought, high salinity and chilling. Chloroplast-localized isoforms of ascorbate peroxidase and possibly peroxiredoxins assume the principal role of scavenging hydrogen peroxide. However, in vitro studies revealed that both types of peroxidases are easily damaged by hydrogen peroxide and lose their catalytic activities. This is one contributing factor for cellular damage that occurs under severe oxidative stress. In this review, I describe mechanisms of hydrogen peroxide-mediated inactivation of these two enzymes and discuss a reason why they became susceptible to damage by hydrogen peroxide.