Lead Structures for Applications in Photodynamic Therapy. Part 3.
Temoporfin (Foscan®, 5,10,15,20-Tetra(m-hydroxyphenyl)chlorin)—A Second-generation Photosensitizer
Article first published online: 19 SEP 2011
© 2011 The Authors. Photochemistry and Photobiology © 2011 The American Society of Photobiology
Photochemistry and Photobiology
Volume 87, Issue 6, pages 1240–1296, November/December 2011
How to Cite
Senge, M. O. and Brandt, J. C. (2011), Temoporfin (Foscan®, 5,10,15,20-Tetra(m-hydroxyphenyl)chlorin)—A Second-generation Photosensitizer. Photochemistry and Photobiology, 87: 1240–1296. doi: 10.1111/j.1751-1097.2011.00986.x
Dedicated to Professor Ray Bonnett.
- Issue published online: 21 OCT 2011
- Article first published online: 19 SEP 2011
- Accepted manuscript online: 16 AUG 2011 09:19AM EST
- Received 27 May 2011, accepted 5 August 2011
This review traces the development and study of the second-generation photosensitizer 5,10,15,20-tetra(m-hydroxyphenyl)chlorin through to its acceptance and clinical use in modern photodynamic (cancer) therapy. The literature has been covered up to early 2011.