Photosensitizing Mechanism and Identification of Levofloxacin Photoproducts at Ambient UV Radiation
Article first published online: 25 JAN 2012
© 2011 Wiley Periodicals, Inc. Photochemistry and Photobiology © 2011 The American Society of Photobiology
Photochemistry and Photobiology
Volume 88, Issue 2, pages 344–355, March/April 2012
How to Cite
Dwivedi, A., Mujtaba, S. F., Kushwaha, H. N., Ali, D., Yadav, N., Singh, S. K. and Ray, R. S. (2012), Photosensitizing Mechanism and Identification of Levofloxacin Photoproducts at Ambient UV Radiation. Photochemistry and Photobiology, 88: 344–355. doi: 10.1111/j.1751-1097.2011.01068.x
- Issue published online: 1 MAR 2012
- Article first published online: 25 JAN 2012
- Accepted manuscript online: 29 DEC 2011 02:52PM EST
- Received 7 September 2011, accepted 15 December 2011
Figure S1. Photodegradation spectra of LVFX (25& μg mL−1) under sunlight (60–240& min).
Figure S2. Percent photochemical quenching of 1O2 at 50& μg mL−1 LVFX by DABCO and NaN3 under UV-A (7.92& J cm−2), UV-B (3.24& J cm−2) and sunlight exposure (60& min). Values are mean of three observations ±SD.
Figure S3. Percent quenching of O2•− at 50& μg mL−1 LVFX by superoxide dismutase (SOD), under UV-A (2.64& J cm−2), UV-B (1.08& J cm−2 and sunlight (20& min). Values presented are mean of three observations ±SD.
Figure S4. Percent photochemical quenching of •OH at 50& μg mL−1 LVFX by mannitol under UV-A (7.92& J cm−2), UV-B (3.24& J cm−2) and sunlight exposure (60& min). Values are mean of three observations ±SD.
Figure S5. The EB/AO staining method was used to assess the cell status after the treatment with LVFX alone or in combination with UV-A (2.16& J cm−2) and incubated for 18& hrs (a) Dark control presence of HBSS alone (b) Dark control presence of LVFX (100& μg/mL), (c) Sample UV-A irradiated in presence of HBSS (d) Sample UV-A irradiated in presence of LVFX (25& μg mL−1) and (e) Sample UV-A irradiated in presence of LVFX (100& μg mL−1).
|PHP_1068_sm_FigS1.tif||2087K||Supporting info item|
|PHP_1068_sm_FigS2.tif||1081K||Supporting info item|
|PHP_1068_sm_FigS3.tif||1081K||Supporting info item|
|PHP_1068_sm_FigS4.tif||1081K||Supporting info item|
|PHP_1068_sm_FigS5.tif||2087K||Supporting info item|
Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.