Current address: Department of Molecular and Cell Biology, Beckman Research Institute of the City of Hope, Duarte, CA, USA.
The (α-4) Photoconjugates of 5-Methylcytosine, 1,5-Dimethylcytosine, 1-Methylthymine and Thymidine
Article first published online: 23 JAN 2012
© 2011 Wiley Periodicals, Inc. Photochemistry and Photobiology © 2011 The American Society of Photobiology
Photochemistry and Photobiology
Volume 88, Issue 2, pages 336–343, March/April 2012
How to Cite
Shetlar, M. D. and Chung, J. (2012), The (α-4) Photoconjugates of 5-Methylcytosine, 1,5-Dimethylcytosine, 1-Methylthymine and Thymidine. Photochemistry and Photobiology, 88: 336–343. doi: 10.1111/j.1751-1097.2011.01070.x
- Issue published online: 1 MAR 2012
- Article first published online: 23 JAN 2012
- Accepted manuscript online: 29 DEC 2011 02:53PM EST
- Received 17 October 2011, accepted 21 December 2011
Appendix S1. Experimental details of the preparation and purification protocols for various photoproducts and descriptions of the partial characterizations of certain photoproducts of 5-methyl-2′-deoxycytidine.
Figure S1. The UV spectra of the “dh” products of 1,5-dimethylcytosine (Ib) and 1-methylthymine (IIb).
Figure S2. The UV spectra of three other photoproducts of 1,5-dimethylcytosine.
Figure S3. The UV spectra of the “dh” products of 5-methyl-2′-deoxycytidine (putatively Ic) and thymidine (IIc).
Figure S4. The proton NMR spectrum of the “dh” product of Thd (IIc).
Figure S5. The chromatogram resulting from HPLC of 5-MedCyd, irradiated at 254 nm in frozen aqueous solution.
Figure S6. The proton NMR spectrum of the “dh” product of 5-MedCyd.
Figure S7. The UV spectra of three 5-MedCyd photoproducts with either tentatively assigned or unassigned structures.
Figure S8. A possible mechanism leading to formation of the “spore” photoproducts of Thd.
Table S1. Correlations between compound designations (e.g. PH11), structural assignments (e.g.IIc) and compound type (e.g. Thd [α-4] conjugate).
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