A Novel Pathway of Photoinduced Decomposition of Sphingolipids


Corresponding author email: shadyro@open.by (Oleg I. Shadyro)


A possibility of a novel photodestruction process has been shown for sphingolipids and their low-molecular analogues, including the stage of Norrish Type-I decomposition of excited molecules of the starting compounds followed by fragmentation of nitrogen-centered radicals via rupture of the C–C and O–H bonds. Realization of such transformation during photolysis of ceramide, sphingomyelin and galactocerebroside results in formation of 2-hexadecenal, which possess a wide spectrum of biological activity.