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The Effects of UV Emission from Compact Fluorescent Light Exposure on Human Dermal Fibroblasts and Keratinocytes In Vitro

Authors

  • Tatsiana Mironava,

    Corresponding author
    1. Department of Materials Science and Engineering, State University of New York at Stony Brook, Stony Brook, NY
      Corresponding author email: tania.mironova@gmail.com (Tatsiana Mironava)
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  • Michael Hadjiargyrou,

    1. Department of Biomedical Engineering, State University of New York at Stony Brook, Stony Brook, NY
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  • Marcia Simon,

    1. Department of Oral Biology and Pathology, School of Dental Medicine, State University of New York at Stony Brook, Stony Brook, NY
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  • Miriam H. Rafailovich

    1. Department of Materials Science and Engineering, State University of New York at Stony Brook, Stony Brook, NY
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Corresponding author email: tania.mironova@gmail.com (Tatsiana Mironava)

Abstract

Compact fluorescent light (CFL) bulbs can provide the same amount of lumens as incandescent light bulbs, using one quarter of the energy. Recently, CFL exposure was found to exacerbate existing skin conditions; however, the effects of CFL exposure on healthy skin tissue have not been thoroughly investigated. In this study, we studied the effects of exposure to CFL illumination on healthy human skin tissue cells (fibroblasts and keratinocytes). Cells exposed to CFLs exhibited a decrease in the proliferation rate, a significant increase in the production of reactive oxygen species, and a decrease in their ability to contract collagen. Measurements of UV emissions from these bulbs found significant levels of UVC and UVA (mercury [Hg] emission lines), which appeared to originate from cracks in the phosphor coatings, present in all bulbs studied. The response of the cells to the CFLs was consistent with damage from UV radiation, which was further enhanced when low dosages of TiO2 nanoparticles (NPs), normally used for UV absorption, were added prior to exposure. No effect on cells, with or without TiO2 NPs, was observed when they were exposed to incandescent light of the same intensity.

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