Human papillomavirus (HPV) is associated with several types of cancer in both women and men, including cervical cancer, anal cancer and head and neck cancer. Public health efforts to educate consumers about HPV and vaccination have largely focused on women. This article summarizes three recent studies in which researchers examined issues regarding male attitudes and acceptance of the human papillomavirus (HPV) vaccine. All three papers suggest that vaccination of males would be beneficial to both men and women in reducing the overall HPV-related health burden. Here, the three studies are summarized and evaluated, and implications for nursing practice are discussed.