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Keywords:

  • Cryoglobulinemia;
  • cytology;
  • peripheral blood;
  • body fluid

Summary

Laboratory identification of cytoplasmic inclusions in leucocytes as unusual manifestation of cryoglobulinemia has been previously reported (Maitra et al., 2000 American Journal of Clinical Pathology, 113, 107–112; Fohlen-Walter et al., 2002American Journal of Clinical Pathology, 117, 606–614.). We would like to add two observations highlighting the following: (i) the peculiar picture of cryoglobulins in neutrophils and monocytes but sparing other white blood cell (WBC) and (ii) possibility of deposit occurrence with morphological identification in body fluids.