Transcranial Doppler Blood Flow Assessment in Patients With Mild Heart Failure: Correlates With Neuroimaging and Cognitive Performance

Authors

  • Raymond L. C. Vogels MD,

    1. From the Department of Neurology, Sint Lucas-Andreas Hospital;1the Department of Neurology and Alzheimer Center, VU Medical Center;2the Department of Clinical Neuropsychology, VU University;3Department of Clinical Neurophysiology, Sint Lucas-Andreas Hospital;4 and the Department of Cardiology, Sint Lucas-Andreas Hospital,5 Amsterdam, the Netherlands
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  • 1,2 Joukje M. Oosterman PhD,

    1. From the Department of Neurology, Sint Lucas-Andreas Hospital;1the Department of Neurology and Alzheimer Center, VU Medical Center;2the Department of Clinical Neuropsychology, VU University;3Department of Clinical Neurophysiology, Sint Lucas-Andreas Hospital;4 and the Department of Cardiology, Sint Lucas-Andreas Hospital,5 Amsterdam, the Netherlands
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  • 3 David M. Laman MD, PhD,

    1. From the Department of Neurology, Sint Lucas-Andreas Hospital;1the Department of Neurology and Alzheimer Center, VU Medical Center;2the Department of Clinical Neuropsychology, VU University;3Department of Clinical Neurophysiology, Sint Lucas-Andreas Hospital;4 and the Department of Cardiology, Sint Lucas-Andreas Hospital,5 Amsterdam, the Netherlands
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  • 4 Alida A. Gouw MD,

    1. From the Department of Neurology, Sint Lucas-Andreas Hospital;1the Department of Neurology and Alzheimer Center, VU Medical Center;2the Department of Clinical Neuropsychology, VU University;3Department of Clinical Neurophysiology, Sint Lucas-Andreas Hospital;4 and the Department of Cardiology, Sint Lucas-Andreas Hospital,5 Amsterdam, the Netherlands
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  • 2 Jutta M. Schroeder-Tanka MD, PhD,

    1. From the Department of Neurology, Sint Lucas-Andreas Hospital;1the Department of Neurology and Alzheimer Center, VU Medical Center;2the Department of Clinical Neuropsychology, VU University;3Department of Clinical Neurophysiology, Sint Lucas-Andreas Hospital;4 and the Department of Cardiology, Sint Lucas-Andreas Hospital,5 Amsterdam, the Netherlands
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  • 5 Philip Scheltens MD, PhD,

    1. From the Department of Neurology, Sint Lucas-Andreas Hospital;1the Department of Neurology and Alzheimer Center, VU Medical Center;2the Department of Clinical Neuropsychology, VU University;3Department of Clinical Neurophysiology, Sint Lucas-Andreas Hospital;4 and the Department of Cardiology, Sint Lucas-Andreas Hospital,5 Amsterdam, the Netherlands
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  • 2 Wiesje M. Van Der Flier PhD,

    1. From the Department of Neurology, Sint Lucas-Andreas Hospital;1the Department of Neurology and Alzheimer Center, VU Medical Center;2the Department of Clinical Neuropsychology, VU University;3Department of Clinical Neurophysiology, Sint Lucas-Andreas Hospital;4 and the Department of Cardiology, Sint Lucas-Andreas Hospital,5 Amsterdam, the Netherlands
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  • and 2 Henry C. Weinstein MD, PhD 1

    1. From the Department of Neurology, Sint Lucas-Andreas Hospital;1the Department of Neurology and Alzheimer Center, VU Medical Center;2the Department of Clinical Neuropsychology, VU University;3Department of Clinical Neurophysiology, Sint Lucas-Andreas Hospital;4 and the Department of Cardiology, Sint Lucas-Andreas Hospital,5 Amsterdam, the Netherlands
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Raymond L. C. Vogels, MD, Department of Neurology, VU Medical Center, PO Box 7057, 1007 MB Amsterdam, the Netherlands
E-mail: r.vogels@vumc.nl

Abstract

Cardiac output and cerebral perfusion are reduced in patients with advanced stages of heart failure. Our aim was to determine whether cerebral blood flow velocity measured by transcranial Doppler ultrasonography was reduced in outpatients with mild heart failure in comparison to controls and, if so, whether this reduction was related to cognitive performance and abnormalities of the brain diagnosed by magnetic resonance imaging.

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