Presented at the Annual Scientific Meeting of the American Heart Association on November 18, 2009.
Incidence of Myocardial Infarction or Stroke or Death at 47-Month Follow-Up in Patients With Diabetes and a Predicted Exercise Capacity ≤85% vs >85% During an Exercise Treadmill Sestamibi Stress Test
Article first published online: 9 NOV 2009
© 2009 Wiley Periodicals, Inc.
Volume 13, Issue 1, pages 14–17, Winter 2010
How to Cite
Pierre-Louis, B., Aronow, W. S., Yoon, J. H., Ahn, C., DeLuca, A. J., Weiss, M. B., Kalapatapu, K., Pucillo, A. L. and Monsen, C. E. (2010), Incidence of Myocardial Infarction or Stroke or Death at 47-Month Follow-Up in Patients With Diabetes and a Predicted Exercise Capacity ≤85% vs >85% During an Exercise Treadmill Sestamibi Stress Test. Preventive Cardiology, 13: 14–17. doi: 10.1111/j.1751-7141.2009.00051.x
- Issue published online: 14 DEC 2009
- Article first published online: 9 NOV 2009
- Manuscript received July 5, 2009; revised August 13, 2009; accepted August 31, 2009
A treadmill exercise sestamibi stress test (TESST) was performed in 609 consecutive diabetic persons with a mean age of 70 years and no history of coronary artery disease (CAD) who were referred for a TESST because of chest pain or dyspnea. Of 609 patients, 301 (49%) had a predicted exercise capacity ≤85% (group A) and 308 (51%) had a predicted exercise capacity >85% (group B). Group A patients had a higher prevalence of myocardial ischemia (43% vs 30%, P=.0005), 2- or 3-vessel obstructive CAD (38% vs 18%, P=.001), myocardial infarction (17% vs 9%, P=.004), death (10% vs 4%, P=.008), and myocardial infarction or stroke or death at 47-month follow-up (21% vs 12%, P=.001). Stepwise Cox regression analysis showed that the only significant independent predictor for the time to development of myocardial infarction or stroke or death was a predicted exercise capacity >85% (hazard ratio, 0.52; 95% confidence interval, 0.34–0.78; P=.002). Diabetic persons with a predicted exercise capacity >85% had a 48% lower chance of myocardial infarction, stroke, or death than those with a predicted exercise capacity ≤85%.
Prev Cardiol. 2010;13:14–17.©2009 Wiley Periodicals, Inc.