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- EVIDENCE SEARCH AND ACQUISITION
- EVIDENCE FOR BENEFITS OF BP-LOWERING IN 65- TO 79-YEAR-OLD PATIENTS
- EVIDENCE FOR BENEFITS OF BP-LOWERING IN PATIENTS 80 YEARS AND OLDER
- PREHYPERTENSION IS A RISK FACTOR FOR CV DISEASE
- INITIAL DRUG THERAPY FOR THE TREATMENT OF HTN IN OLDER ADULTS
- BENEFITS OF NEWER ANTIHYPERTENSIVE MEDICATIONS
Hypertension in older adults is not well controlled in clinical practice. Isolated systolic hypertension is often more difficult to manage. A systematic PubMed search was conducted to look for evidence showing benefits of lowering blood pressure (BP) in older hypertensive adults. Lowering BP in these individuals significantly reduces the risk of coronary artery disease, stroke, and cardiovascular and all-cause mortality. Based on trial evidence, a low-dose diuretic should be considered the most appropriate first-step treatment for preventing cardiovascular morbidity and mortality. Therapy with >1 medication is often necessary to reduce BP in these patients. There is unequivocal evidence that cardiovascular events can be prevented in older adults, even those older than 80 years, by treating hypertension.