STATE OF THE ART REVIEW PAPER
Neurocognitive Alterations in Hypertensive Children and Adolescents
Article first published online: 21 MAY 2012
© 2012 Wiley Periodicals, Inc.
The Journal of Clinical Hypertension
Volume 14, Issue 6, pages 353–359, June 2012
How to Cite
Lande, M. B., Kupferman, J. C. and Adams, H. R. (2012), Neurocognitive Alterations in Hypertensive Children and Adolescents. The Journal of Clinical Hypertension, 14: 353–359. doi: 10.1111/j.1751-7176.2012.00661.x
- Issue published online: 4 JUN 2012
- Article first published online: 21 MAY 2012
- Manuscript received: April 1, 2012; Accepted: April 9, 2012
J Clin Hypertens (Greenwich). 2012; 14:353–359. ©2012 Wiley Periodicals, Inc.
Hypertensive adults demonstrate performance deficits on neuropsychological testing compared with scores of normotensive controls. This article reviews emerging preliminary evidence that children with hypertension also manifest neurocognitive differences when compared with normotensive controls. Database and single-center studies suggest that children with hypertension manifest deficits on measures of neurocognition and have an increased prevalence of learning difficulties and that children with hypertension associated with obesity may be at increased risk for depression and anxiety. Studies suggesting blunted cerebrovascular reactivity in children with hypertension are also reviewed.