• Please log in or register to access this feature.

Original Article

Screening for bipolar disorder in adolescents with the Mood Disorder Questionnaire – Adolescent version (MDQ-A) and the Child Bipolar Questionnaire (CBQ)

  1. Melissa Miguez1,
  2. Béatrice Weber2,
  3. Martin Debbané1,5,
  4. Dario Balanzin1,
  5. Marianne Gex-Fabry3,
  6. Fulvia Raiola1,
  7. Rémy P. Barbe4,
  8. Marylène Vital Bennour4,
  9. François Ansermet4,
  10. Stephan Eliez1,
  11. Jean-Michel Aubry2,*

Article first published online: 26 AUG 2012

DOI: 10.1111/j.1751-7893.2012.00388.x

Additional Information

How to Cite

Miguez, M., Weber, B., Debbané, M., Balanzin, D., Gex-Fabry, M., Raiola, F., Barbe, R. P., Vital Bennour, M., Ansermet, F., Eliez, S. and Aubry, J.-M. (2012), Screening for bipolar disorder in adolescents with the Mood Disorder Questionnaire – Adolescent version (MDQ-A) and the Child Bipolar Questionnaire (CBQ). Early Intervention in Psychiatry. doi: 10.1111/j.1751-7893.2012.00388.x

Author Information

  1. 1

    Office Médico-Pédagogique, University of Geneva, Geneva, Switzerland

  2. 2

    Department of Mental Health and Psychiatry, Bipolar Program, University of Geneva, Geneva, Switzerland

  3. 3

    Department of Mental Health and Psychiatry, University of Geneva, Geneva, Switzerland

  4. 4

    Service of Child and Adolescent Psychiatry, Geneva University Hospitals, University of Geneva, Geneva, Switzerland

  5. 5

    Adolescence Clinical Psychology Research Unit, Faculty of Psychology, University of Geneva, Geneva, Switzerland

*Corresponding author: Dr Jean-Michel Aubry, Department of Mental Health and Psychiatry, Bipolar Program, Geneva University Hospitals, 8, rue du 31 Décembre, 1207 Geneva, Switzerland. Email: jean-michel.aubry@hcuge.ch

Publication History

  1. Article first published online: 26 AUG 2012
  2. Manuscript Accepted: 26 MAY 2012
  3. Manuscript Received: 17 NOV 2011

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article (HTML) Get PDF (379K)

Keywords:

  • adolescent;
  • bipolar disorder;
  • co-morbidity;
  • early diagnosis;
  • questionnaire

Abstract

Aim

Screening instruments for bipolar disorders (BDs) in children and adolescents have been developed recently. The present study examined performances of the French versions of the Mood Disorder Questionnaire – Adolescent version (MDQ-A) and Child Bipolar Questionnaire (CBQ) in a sample of in- and outpatients.

Methods

Seventy-six adolescents (age 13–18) and parents first completed the MDQ-A (adolescent and parent versions) and CBQ screening instruments. About 3 weeks later, they had a diagnostic interview with the Kiddie-Schedule for Affective Disorders and Schizophrenia – Present and Lifetime (K-SADS-PL), and the adolescent MDQ-A self-report was completed a second time.

Results

Eight of 76 patients (10.5%) met K-SADS-PL diagnostic criteria for BD. Test–retest reliability of the adolescent MDQ-A self-report was moderate (kappa = 0.66), whereas agreement between adolescent and parent reports was poor (kappa = 0.07). Sensitivity and specificity of the MDQ-A with respect to K-SADS-PL were 75.0% and 57.4% for the adolescent version, and 87.5% and 63.2% for the parent version. Corresponding figures were 50.0% and 73.5% for the CBQ. All three screening instruments had low positive predictive values (17.1% for the MDQ-A adolescent version; 21.9% for the MDQ-A parent version; 18.2% for the CBQ), whereas negative predictive values were higher than 90%.

Conclusions

The present study points to modest performances of the MDQ-A and CBQ to detect BDs in adolescents, with diagnostic criteria for BD being unmet for a majority of patients who screened positive.

View Full Article (HTML) Get PDF (379K)