• Open Access

Microbial biotechnology for producing high volume chemicals

An annotated selection of World Wide Web sites relevant to the topics in Microbial Biotechnology

Authors

  • Lawrence P. Wackett

    1. McKnight Professor and Head
      Microbial Biochemistry and Biotechnology
      Department of Biochemistry
      Molecular Biology and Biophysics
      University of Minnesota
      St Paul, MN 55108, USA
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New biocatalysts

http://www1.eere.energy.gov/biomass/pdfs/biocatalysis_roadmap.pdf

This web publication discusses biocatalysis for producing high volume chemicals from renewable resources. It is released by the U.S. Department of Energy.

Glycerol to commodity chemicals

http://www.rsc.org/ej/CS/2008/b707343g.pdf

Glycerol is a byproduct of biodiesel manufacture and that has caused a large decrease in its cost. Novel conversion routes for glycerol to commodity chemicals will make biomass utilization more efficient and profitable.

EPA green chemistry awardees

http://www.epa.gov/greenchemistry/pubs/pgcc/technology.html

This site lists the green chemistry awardees. Most of the green processes are novel biocatalytic routes to chemicals.

Chemicals from biomass

http://www.sciencemag.org/cgi/content/full/318/5854/1250

This article discusses the past, present and future of producing chemicals from biomass by biocatalysis.

Method for the production of isobutanol

http://www.freshpatents.com/Method-for-the-production-of-isobutanol-dt20081106ptan20080274526.php

This patent describes a biological process for making isobutanol using recombinant bacteria. Isobutanol can be chemical modified to make a range of fuels and chemicals.

Benzene free routes to aromatics

http://www.frostchemlab.com/green-Synthesis.htm

Fermentation proceses can be used to make aromatic ring compounds in reasonably high yield. This offers an alternative to petroleum-based feedstocks for benzene and its derivatives.

1,3-Propanediol: Wikipedia

http://en.wikipedia.org/wiki/1,3-Propanediol

1,3-Propanediol is used in large quantities for making industrial carpets. Genencor and DuPont teamed up to develop an industrial process to make 1,3-propanediol in a genetically-engineered E. coli strain.

Acrylic acid from 3-hydroxypropionic acid

http://www.cargill.com/news/news_releases/080114_novozymes.htm

3-Hydroxypropionic acid is a biologically produced platform chemical. It can be dehydrated to produce the valuable commodity chemical acrylic acid.

Next generation fermentation

http://www.ornl.gov/info/ornlreview/v40_1_07/article06.shtml

Most ethanol today is produced via a microbial fermentation process. This document details some of the current issues relevant to this process.

Acetic acid: Wikipedia

http://en.wikipedia.org/wiki/Acetic_acid

Acetic acid is mostly made chemically from petroleum precursors. Some, for foods, are produced biologically.

Acrylonitrile pathway map

http://umbbd.msi.umn.edu/acr/acr_map.html

The acrylonitrile pathway shows metabolic transformations leading from acrylonitrile to acrylamide and acrylic acid.

Branched chain alcohols: Biological production

http://www.biofuelsdatabase.org/map/BC-alcohols_map.shtml

This page from the BioFuels Database highlights reactions leading to the formation of various branched chain alcohols that have potential usefulness as fuels or chemical feedstocks.

Epichlorohydrin from glycerol

http://www.solvaychemicals.com/info/0,0,1000574-_EN,00.html

This page describes a chemical process to generate epichlorohydrin from glycerol that is obtained from biomass.

New chemistries and processes

http://books.nap.edu/openbook.php?record_id=11437&page=41

This webpage is part of an e-book on sustainability in the chemical industry.

Biomass to chemical publications

http://www1.eere.energy.gov/biomass/publications.html#biochemical

This webpage from the U.S. Department of Energy provides links to e-documents pertaining to conversions of biomass to chemicals and fuels.

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