• Open Access

Biocatalysis and whole cell biotransformations

An annotated selection of World Wide Web sites relevant to the topics in Microbial Biotechnology


  • Lawrence P. Wackett

    1. McKnight Professor
      Microbial Biochemistry and Biotechnology
      Department of Biochemistry
      Molecular Biology and Biophysics
      University of Minnesota
      St Paul, MN 55108, USA
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Organic chemistry and biocatalysis


This commercial website offers publications and links to a range of uses of biocatalysis in organic synthesis.



This page offers a nice tutorial on biocatlysis with some references provided at the end.

Biocatalysis database


The biocatalysis and biodegradation database provides information on organisms, enzymes and metabolic pathways involved in the biotransformation of diverse organic and organometallic compounds.

The lipase engineering database


The database offers information on the sequences and structures of proteins having the alpha-beta hydrolase fold that are of interest commercially. A major grouping of enzymes in this class are the lipases.

Biocat collection


The Biocat collection is a repository of organisms and enzymes that are available for screening or other uses in biocatalysis. The collection includes oxidoreductases, hydrolases, lyases and polymerases.



BRENDA is a comprehensive database of enzymes organized with practical usage in mind. There is extensive information of how to express and obtain maximal enzyme activity.

BASF – Biocatalysis


This page contains information on biocatalysis at BASF and also general, broadly useful, information on the topic.

Biotransformations: Book reviews


Important books on biocatalysis in organic synthesis are reviewed here.

The twelve green chemistry principles


The 12 fundamental principles of green chemistry, as articulated by Paul Anastas, are listed here. Biocatalysis fulfills many of these principles.

Biochemical periodic table


The biochemical periodic table consists of a chemical table with links to biocatalytic transformations relevant to each element. Most of the chemical elements are covered.

MEROPS peptidase database


MEROPS is a resource for information on peptidases, also known as proteases, proteinases or proteolytic enzymes.

Cytochrome P450 homepage


Cytochrome P450 enzymes are monooxygenases that are sometimes of value in biotransformations, often for hydrophobic compounds like steroids.

Glycoside hydrolases database


Glycoside hydrolases have commercial significance, particularly in the transformation of biomass into fermentable sugars.

BioFuels Database


The biofuels database contains information on chemical and biochemical processes for generating fuels from renewable resources.

Functional group biotransformations


The functional group list here is clickable to provide users with information on biotransformation reactions for 60 functional groups.