The aim of this paper is to outline a platform for research on adolescents’ life regulation. Adolescents’ brain development is described with the help of neuroscience and integrated with pragmatist and symbolic interactionist insights about how adolescents can learn to control their impulses and act thoughtfully. The foundation for the analysis is found in American pragmatism, where a biopsychosocial perspective is built on the understanding that the developed human brain is the essential precondition of a complex and civilized society. Today's interactionists, and in general, the majority of sociologists, show little interest in brain development and function. However, there is an opportunity for sociologists and neuroscientists to collaborate in order to better understand how the brain develops in relation to biological development and social experience.