Emerging professional and cultural developments underscore the importance of spiritual assessment. Most marriage and family therapists, however, appear to have received little training on the topic. Consequently, this article overviews a complementary family of six recently developed qualitative assessment approaches or tools, an initial brief assessment tool and five comprehensive assessment tools, and presents a methodological framework for using the six tools. To help decide whether or not a comprehensive assessment is warranted after conducting an initial brief assessment, two general guidelines are offered. Suggestions for selecting the appropriate comprehensive assessment tool are also presented, and summarized graphically in the form of a decision tree. The overall methodological framework is designed to be congruent with the recent spiritual assessments recommendations issued by the Joint Commission on Accreditation of Healthcare Organizations (JCAHO), the largest healthcare accrediting organization in the United States.