ABSTRACT: This study presents a methodology to evaluate the vulnerability of water resources in the Tsengwen creek watershed, Taiwan. Tsengwen reservoir, located in the Tsengwen creek watershed, is a multipurpose reservoir with a primary function to supply water for the ChiaNan Irrigation District. A simulation procedure was developed to evaluate the impacts of climate change on the water resources system. The simulation procedure includes a streamflow model, a weather generation model, a sequent peak algorithm, and a risk assessment process. Three climate change scenarios were constructed based on the predictions of three General Circulation Models (CCCM, GFDL, and GISS). The impacts of climate change on streamflows were simulated, and, for each climate change scenario, the agricultural water demand was adjusted based on the change of potential evapotranspiration. Simulation results indicated that the climate change may increase the annual and seasonal streamflows in the Tsengwen creek watershed. The increase in streamflows during wet periods may result in serious flooding. In addition, despite the increase in streamflows, the risk of water deficit may still increase from between 4 and 7 percent to between 7 and 13 percent due to higher agricultural water demand. The simulation results suggest that the reservoir capacity may need to be expanded. In response to the climate change, four strategies are suggested: (1) strengthen flood mitigation measures, (2) enhance drought protection strategies, (3) develop new water resources technology, and (4) educate the public.