High Density GWAS for LDL Cholesterol in African Americans Using Electronic Medical Records Reveals a Strong Protective Variant in APOE
Article first published online: 23 AUG 2012
© 2012 Wiley Periodicals, Inc.
Clinical and Translational Science
Volume 5, Issue 5, pages 394–399, October 2012
How to Cite
Rasmussen-Torvik, L. J., Pacheco, J. A., Wilke, R. A., Thompson, W. K., Ritchie, M. D., Kho, A. N., Muthalagu, A., Hayes, M. G., Armstrong, L. L., Scheftner, D. A., Wilkins, J. T., Zuvich, R. L., Crosslin, D., Roden, D. M., Denny, J. C., Jarvik, G. P., Carlson, C. S., Kullo, I. J., Bielinski, S. J., McCarty, C. A., Li, R., Manolio, T. A., Crawford, D. C. and Chisholm, R. L. (2012), High Density GWAS for LDL Cholesterol in African Americans Using Electronic Medical Records Reveals a Strong Protective Variant in APOE. Clinical and Translational Science, 5: 394–399. doi: 10.1111/j.1752-8062.2012.00446.x
- Issue published online: 16 OCT 2012
- Article first published online: 23 AUG 2012
Figure S1. (A) QQ plot for LDL GWAS in dataset with exclusions. Genomic inflation factor for this analysis is equal to 1.0. (B) QQ plot for LDL GWAS in dataset with no lab values excluded. Genomic inflation factor for this analysis is equal to 1.0.
Figure S2. LD/association plot of APOE region from LDL GWAS in dataset with exclusions.
Table S1. Association of LDL-C with three SNPs identified in a previous African American GWAS of LDL-C for the eMERGE African American datasets
Table S2. Details of SNPs from the APOE region previously detected in LDL GWAS
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