The findings and conclusions in this article are those of the authors and do not represent the official position of the Centers for Disease Control and Prevention.
Prevalence and correlates of metabolic syndrome based on a harmonious definition among adults in the US*
Article first published online: 23 APR 2010
Published 2010. This article is a US Government work and is in the public domain in the USA
Journal of Diabetes
Volume 2, Issue 3, pages 180–193, September 2010
How to Cite
FORD, E. S., LI, C. and ZHAO, G. (2010), Prevalence and correlates of metabolic syndrome based on a harmonious definition among adults in the US. Journal of Diabetes, 2: 180–193. doi: 10.1111/j.1753-0407.2010.00078.x
- Issue published online: 16 AUG 2010
- Article first published online: 23 APR 2010
- Received 20 January 2010; revised 8 April 2010; accepted 11 April 2010.
- metabolic syndrome;
- population surveillance;
- public health surveillance;
- risk factors
Background: Recently, a Joint Scientific Statement bridged differences between previous definitions of metabolic syndrome. Our objective was to estimate the prevalence of metabolic syndrome in a representative sample of US adults and to examine its correlates.
Methods: We analyzed data for up to 3461 participants aged ≥20 years of the 2003–2006 National Health and Nutrition Examination Survey.
Results: Using waist circumference thresholds of ≥102 cm for men and ≥88 cm for women, the age-adjusted prevalence of metabolic syndrome was 34.3% among all adults, 36.1% among men, and 32.4% among women. Using racial- or ethnic-specific International Diabetes Federation criteria for waist circumference, the age-adjusted prevalence of metabolic syndrome was 38.5% for all participants, 41.9% for men, and 35.0% for women. Prevalence increased with age, peaking among those aged 60–69 years. Prevalence was lower among African American men than White or Mexican American men, and lower among White women than among African American or Mexican American women. In a multivariate regression model, significant independent associations were noted for age (positive), gender (men higher than women), race or ethnicity (African Americans and participants of another race lower than Whites), educational status (inverse), hypercholesterolemia (positive), concentrations of C-reactive protein (positive), leisure time physical activity (inverse), microalbuminuria (positive), and hyperinsulinemia (positive). Additional adjustment for body mass index weakened many of the associations, with educational status and microalbuminuria no longer significant contributors to the model.
Conclusion: Metabolic syndrome continues to be highly prevalent among adults in the US.