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Keywords:

  • tryptophan;
  • phenylalanine;
  • tyrosine;
  • branched-chain amino acids;
  • regulation of brain nutrition;
  • membrane transport;
  • blood-brain barrier;
  • albumin-bound tryptophan

Entry of tryptophan, tyrosine and related amino acids into brain depends on their competition for transport System L at the blood-brain barrier. Specific binding of tryptophan by serum albumin presents an added point of regulation.