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Cross-talk of human gut with bifidobacteria

Authors

  • Ilja Trebichavsky,

    1. Division of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, Novy Hradek, Czech Republic
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  • Vojtech Rada,

    1. Department of Microbiology, Nutrition and Dietetics, Czech University of Agriculture Prague, Prague, Czech Republic
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  • Alla Splichalova,

    1. Division of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, Novy Hradek, Czech Republic
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  • Igor Splichal

    1. Division of Immunology and Gnotobiology, Institute of Microbiology, Academy of Sciences of the Czech Republic, Novy Hradek, Czech Republic
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I Splichal, Institute of Microbiology, AS CR, Doly 183, 549 22 Novy Hradek, Czech Republic. E-mail: splichal@biomed.cas.cz, Phone: +420-491-418-539, Fax: +420-491-478-264.

Abstract

The gut constitutes a prominent part of the immune system. Its commensal microflora plays an important role in defense and in tolerance to diet allergens. Disturbances in immune regulations may lead to food allergy. Among commensal bacteria, bifidobacteria are able to induce mechanisms of immune tolerance. Comprehension of their mutual cross-talk with the host is necessary for understanding their role in the diet and in food supplements.

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