Palliation of radiation-related mucositis
Article first published online: 12 MAR 2008
Special Care in Dentistry
Volume 10, Issue 1, pages 21–25, January 1990
How to Cite
Rothwell, B. R. and Spektor, W. S. (1990), Palliation of radiation-related mucositis. Special Care in Dentistry, 10: 21–25. doi: 10.1111/j.1754-4505.1990.tb01082.x
- Issue published online: 12 MAR 2008
- Article first published online: 12 MAR 2008
Oral mucositis associated with head and neck radiotherapy can substantially hinder completion of cancer therapy. Alleviation of this often severe stomatitis can provide enhanced patient comfort and facilitate appropriate care.
A double-blind format was used in a pilot project to measure, against a control rinse, the effectiveness of an oral rinse consisting of hydrocortisone, nystatin, tetracycline, and diphenhydramine in controlling radiation-related mucositis. A combination of clinical evaluation and patient responses to a questionnaire was used to judge the results of the topical medications.
Patients using the experimental medication developed less mucositis than did patients in the control group.