Paraneoplastic epidermolysis bullosa acquisita associated with multiple myeloma

Authors

  • Lida Radfar DDS, MS,

    Corresponding author
    1. Assistant Professor of Oral Medicine, Department of Oral Diagnostic Sciences, School of Dental Medicine, State University of New York at Buffalo
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  • Mahnaz Fatahzadeh DMD,

    1. Assistant Professor, Division of Oral Medicine, Department of Diagnostic Sciences, New Jersey Dental School, University of Medicine and Dentistry of New Jersey
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  • Yasaman Shahamat DDS,

    1. Private practice, Greenbelt, Maryland; 4Chairman and Associate Professor, Department Of Oral Medicine, Associate Dean for Graduate Education, New York University, College of Dentistry Department of Oral Medicine
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  • David Sirois DMD, PhD

    1. Assistant Professor of Oral Medicine, Department of Oral Diagnostic Sciences, School of Dental Medicine, State University of New York at Buffalo
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*lradfar@buffalo.edu

ABSTRACT

Epidermolysis bullosa acquisita is a rare acquired autoimmune subepidermal blistering disease that clinically resembles other vesiculobullous lesions such as pemphigus vulgaris and cicatricial pemphigoid. Multiple myeloma is the most common plasma cell malignant disorder characterized by a single clonal expansion and increased level of a single immunoglobulin. Epidermolysis bullosa acquisita has been reported with other systemic diseases such as lymphoma. In this case report, we present a patient with paraneoplastic epidermolysis bullosa acquisita associated with multiple myeloma.

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