• AIDS. disseminated histoplasmosis;
  • deep fungal infection;
  • oral ulcers


Histoplasmosis is a fungal disease that affects humans and is caused by Histoplasma capsulatum. The presentation of the infection may be acute, chronic, or disseminated. The disseminated form has extrapulmonary manifestations which may include oral manifestation a. A patient with AIDS sought treatment and he had disseminated histoplasmosis with oral manifestations.

The purpose of this case report and literature review is to emphasize the role the dental team has in the diagnosis of disseminated disease when a patient presents with oral manifestations associated with the disease.

This case report is clinically relevant because it is not uncommon for oral manifestations to be one of the first signs of systemic disease.