Spec Care Dentist 31(4): 123-128, 2011
In vitro antimicrobial effects of commercially available mouth-wetting agents
Article first published online: 5 JUL 2011
© 2011 Special Care Dentistry Association and Wiley Periodicals, Inc.
Special Care in Dentistry
Volume 31, Issue 4, pages 123–128, July/August 2011
How to Cite
Güneri, P., Alpöz, E., Epstein, J. B., Çankaya, H. and Ates, M. (2011), In vitro antimicrobial effects of commercially available mouth-wetting agents. Special Care in Dentistry, 31: 123–128. doi: 10.1111/j.1754-4505.2011.00194.x
- Issue published online: 5 JUL 2011
- Article first published online: 5 JUL 2011
- dry mouth;
- saliva substitutes;
- antimicrobial effects;
- oral rinse;
- oral gel
Products have been developed to provide palliation for persons with dry mouth. In addition to mouth-wetting agents, some products incorporate antimicrobial constituents with the goal of improving oral microbial defenses. The aim of this in vitro study was to investigate the potential antimicrobial and antifungal effects of two commercially available saliva substitutes on Streptococcus mutans, Lactobacillus acidophilus, and Candida albicans by using the agar-well diffusion method. Antimicrobial activity as measured by the size of the inhibition zone growth for S. mutans and L. acidophilus was observed only with Biotene Dry Mouth Oral Rinse® and BioXtra® gel. The zone of inhibition of Biotene Dry Mouth Oral Rinse was larger than that of BioXtra gel (p= 0.00, p < 0.01). No anticandidal effect was seen with any of the test products. The pH of the preparations, the variations between the amount of active ingredients within the products, and the potential antimicrobial effects of inactive ingredients should be investigated to determine the factors that impacted microbial inhibition.