N Varzeshi MD; M Hansen MBBS, FRANZCR; A Rezaee MD; N Dixon MBBS; E Duhig MBBS, FRCPA; R Slaughter MBBS, FRACR.
Radiology and pathology correlation in common infiltrative cardiomyopathies
Article first published online: 5 DEC 2012
© 2012 The Authors. Journal of Medical Imaging and Radiation Oncology © 2012 The Royal Australian and New Zealand College of Radiologists
Journal of Medical Imaging and Radiation Oncology
Volume 56, Issue 6, pages 628–635, December 2012
How to Cite
Varzeshi, N., Hansen, M., Rezaee, A., Dixon, N., Duhig, E. and Slaughter, R. (2012), Radiology and pathology correlation in common infiltrative cardiomyopathies. Journal of Medical Imaging and Radiation Oncology, 56: 628–635. doi: 10.1111/j.1754-9485.2012.02431.x
Conflict of interest: None declared.
- Issue published online: 5 DEC 2012
- Article first published online: 5 DEC 2012
- Manuscript Accepted: 8 DEC 2011
- Manuscript Received: 20 SEP 2011
- endomyocardial biopsy;
- late gadolinium enhancement;
- magnetic resonance imaging;
Infiltrative cardiomyopathies generally pose a diagnostic dilemma as current diagnostic tools are imprecise. Invasive endomyocardial biopsy is considered as the gold standard however it has some limitations. Recently cardiovascular magnetic resonance (CMR) is emerging as an excellent technique in diagnosing infiltrative cardiomyopathies and is increasingly being used. Characteristic pathologic and radiologic findings in most common infiltrative cardiomyopathies (amyloid, sarcoid and Fabry's) are discussed and correlated with relative CMR and histologic examples. There is fairly good correlation between the non-invasive radiologic and the invasive histologic findings in common infiltrative cardiomyopathies. Non-invasive CMR with its high sensitivity and specificity has an excellent role in establishing the diagnosis and improving the prognosis of common infiltrative cardiomyopathies.