These authors contributed equally to this work.
2BAD: an application to estimate the parental contributions during two independent admixture events
Article first published online: 16 OCT 2009
© 2009 Blackwell Publishing Ltd
Molecular Ecology Resources
Volume 10, Issue 3, pages 538–541, May 2010
How to Cite
BRAY, T. C., SOUSA, V. C., PARREIRA, B., BRUFORD, M. W. and CHIKHI, L. (2010), 2BAD: an application to estimate the parental contributions during two independent admixture events. Molecular Ecology Resources, 10: 538–541. doi: 10.1111/j.1755-0998.2009.02766.x
- Issue published online: 6 APR 2010
- Article first published online: 16 OCT 2009
- Received 30 March 2009; revision received 30 June 2009; accepted 2 August 2009
- approximate Bayesian computation;
- multiple admixture
Several approaches have been developed to calculate the relative contributions of parental populations in single admixture event scenarios, including Bayesian methods. In many breeds and populations, it may be more realistic to consider multiple admixture events. However, no approach has been developed to date to estimate admixture in such cases. This report describes a program application, 2BAD (for 2-event Bayesian ADmixture), which allows the consideration of up to two independent admixture events involving two or three parental populations and a single admixed population, depending on the number of populations sampled. For each of these models, it is possible to estimate several parameters (admixture, effective sizes, etc.) using an approximate Bayesian computation approach. In addition, the program allows comparing pairs of admixture models, determining which is the most likely given data. The application was tested through simulations and was found to provide good estimates for the contribution of the populations at the two admixture events. We were also able to determine whether an admixture model was more likely than a simple split model.