Building the perfect beast: complex mouse models teach surprisingly simple melanoma lessons


  • Coverage on: Dankort, D., Curley, D.P., Cartlidge, R.A., Nelson, B., Karnezis, A.N., Damsky Jr, W.E., You, M.J., Depinho, R.A., McMahon, M. and Bosenberg, M. (2009). BRafV600E cooperates with Pten silencing to elicit metastatic melanoma. Nat. Genet. doi: 10.1038/ng.356.
    Dhomen, N., Reis-Filho, J.S., da Rocha Dias, S., Hayward, R., Savage, K., Delmas, V., Larue, L., Pritchard, C. and Marais, R. (2009). Oncogenic BRAF induces melanocyte senescence and melanoma in mice. Cancer Cell 15, 294–303.

    This article is a US Government work and is in the public domain in the USA.

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