Functional interactions between OCA2 and the protein complexes BLOC-1, BLOC-2, and AP-3 inferred from epistatic analyses of mouse coat pigmentation
Article first published online: 17 DEC 2010
© 2010 John Wiley & Sons A/S
Pigment Cell & Melanoma Research
Volume 24, Issue 2, pages 275–281, April 2011
How to Cite
Hoyle, D. J., Rodriguez-Fernandez, I. A. and Dell’Angelica, E. C. (2011), Functional interactions between OCA2 and the protein complexes BLOC-1, BLOC-2, and AP-3 inferred from epistatic analyses of mouse coat pigmentation. Pigment Cell & Melanoma Research, 24: 275–281. doi: 10.1111/j.1755-148X.2010.00815.x
- Issue published online: 10 MAR 2011
- Article first published online: 17 DEC 2010
- Accepted manuscript online: 2 DEC 2010 05:31AM EST
- PUBLICATION DATA Received 21 September 2010, revised and accepted for publication 29 November 2010, published online 2 December 2010
Figure S1. Estimation of total melanin content in dorsal hair samples from C57BL/6J mice and congenic mutants defective in OCA2 (Oca2p-un), the pallidin subunit of BLOC-1 (Pldnpa), the HPS3 subunit of BLOC-2 (Hps3coa) or the β3A subunit of AP-3 (Ap3b1pe).
Figure S2. Quantification of total melanin content in dorsal hair from female mice carrying the Oca2p-un allele and/or mutant alleles in genes encoding subunits of BLOC-1, BLOC-2 and AP-3.
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