Inhibition of coding region determinant binding protein sensitizes melanoma cells to chemotherapeutic agents
Article first published online: 28 OCT 2011
© 2011 John Wiley & Sons A/S
Pigment Cell & Melanoma Research
Volume 25, Issue 1, pages 83–87, January 2012
How to Cite
Craig, E. A. and Spiegelman, V. S. (2012), Inhibition of coding region determinant binding protein sensitizes melanoma cells to chemotherapeutic agents. Pigment Cell & Melanoma Research, 25: 83–87. doi: 10.1111/j.1755-148X.2011.00921.x
- Issue published online: 16 DEC 2011
- Article first published online: 28 OCT 2011
- Accepted manuscript online: 8 OCT 2011 10:08AM EST
- PUBLICATION DATA Received 25 July 2011, revised and accepted for publication 4 October 2011, published online 8 October 2011
Figure S1 and S2. Detection of phosphatidylserine exposure in the primary melanoma cell lines WM35 and WM115 by annexin V staining.
Figure S3 and S4. Detection of phosphatidylserine exposure in the metastatic melanoma cell lines Skmel2 and Skmel28 by annexin V staining.
Figure S5. Detection of phosphatidylserine exposure in Skmel2 cells using a different sh-CRD-BP construct.
Figure S6. Detection of phosphatidylserine exposure in normal human melanocytes by fluorescence staining.
Figure S7. Disruption of CRD-BP and MITF expression by sh-CRD-BP.
Figure S8. Effect of CRD-BP inhibition and MITF overexpression on the anti-growth response to chemotherapeutics used at low concentrations.
Figure S9. NFκB activation, MDR-1 and c-myc expression in the presence and absence of CRD-BP.
Appendix S1. Methods.
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