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Figure S1. Fibroblasts are resistant to 4-NC action. Human dermal fibroblasts derived from foreskin (FF282, FF284, FF287 and HNF) were treated with 4-NC (10 and 30 μM) for 24 h.

Figure S2. Cell viability measured by Trypan Blue assay.

Figure S3. Evaluation of anti and proapoptotic factors levels in melanocytes, keratinocytes and melanomas at lower concentration of 4-NC.

Figure S4. Cell viability measured by MTT assay.

Figure S5. Effects of 4-NC on the dermal equivalent contraction (normal human fibroblasts (FHN) embedded in type I collagen gel).

FilenameFormatSizeDescription
PCMR_992_sm_figs1.tiff1520KSupporting info item
PCMR_992_sm_figs2.tif5545KSupporting info item
PCMR_992_sm_figs3.tif7375KSupporting info item
PCMR_992_sm_figs4.tif10199KSupporting info item
PCMR_992_sm_figs5.tiff348KSupporting info item

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