Tight orbit syndrome: a previously unrecognized cause of open-angle glaucoma
Article first published online: 15 JAN 2010
© 2010 The Authors. Journal compilation © 2010 Acta Ophthalmol
Volume 88, Issue 1, pages 120–124, February 2010
How to Cite
Lee, G. A., Ritch, R., Liang, S. Y.-W., Liebmann, J. M., Dubois, P., Bastian-Jordan, M., Lehmann, K. and Rojanapongpun, P. (2010), Tight orbit syndrome: a previously unrecognized cause of open-angle glaucoma. Acta Ophthalmologica, 88: 120–124. doi: 10.1111/j.1755-3768.2009.01755.x
- Issue published online: 28 JAN 2010
- Article first published online: 15 JAN 2010
- Received on January 31st, 2009. Accepted on August 6th, 2009.
- intraocular pressure;
Purpose: To describe a new syndrome of tight orbit and intractable glaucoma with a poor visual prognosis.
Methods: A retrospective observational case series of six patients seen at two centres between 2001 and 2007 assessing intraocular pressure (IOP), best-corrected visual acuity and visual field.
Results: Three men and three women, ranging in age at diagnosis from 14 to 53 years, demonstrated similar orbital features and progressive visual field loss despite intensive management with medication and laser and operative surgery. Highest IOPs ranged from 30 to 50 mmHg. Trabeculectomy and/or glaucoma drainage devices were attempted in five patients but all failed. One patient underwent orbital decompression with achievement of IOP control. Final IOP at last follow-up was variable; only two patients achieved IOP in the normal range, with the rest ranging from 25 to 40 mmHg. All patients had advanced visual field loss.
Conclusion: Tight orbit syndrome presents a serious clinical challenge. Despite maximum medical therapy and surgical intervention IOP is difficult to control, resulting in progressive visual field loss.