Femtosecond (FS) laser vision correction procedure for moderate to high myopia: a prospective study of ReLEx® flex and comparison with a retrospective study of FS-laser in situ keratomileusis
Article first published online: 18 APR 2012
© 2012 The Authors. Acta Ophthalmologica © 2012 Acta Ophthalmologica Scandinavica Foundation
Volume 91, Issue 4, pages 355–362, June 2013
How to Cite
Vestergaard, A., Ivarsen, A., Asp, S. and Hjortdal, J. Ø. (2013), Femtosecond (FS) laser vision correction procedure for moderate to high myopia: a prospective study of ReLEx® flex and comparison with a retrospective study of FS-laser in situ keratomileusis. Acta Ophthalmologica, 91: 355–362. doi: 10.1111/j.1755-3768.2012.02406.x
- Issue published online: 30 MAY 2013
- Article first published online: 18 APR 2012
- Received on July 1st, 2011 Accepted on January 13th, 2012.
- corneal higher-order aberrations;
- excimer laser;
- femtosecond laser;
- lenticule extraction;
- myopia, refractive surgery
Purpose: To present our initial clinical experience with ReLEx® flex (ReLEx) for moderate to high myopia. We compare efficacy, safety and corneal higher-order aberrations after ReLEx with femtosecond laser in situ keratomileusis (FS-LASIK).
Methods: Prospective study of ReLEx compared with a retrospective study of FS-LASIK. ReLEx is a new keratorefractive procedure, where a stromal lenticule is cut by a femtosecond laser and manually extracted. Forty patients were treated with ReLEx on both eyes. A comparable group of 41 FS-LASIK patients were retrospectively identified. Visual acuity, spherical equivalent (SE) and corneal tomography were measured before and 3 months after surgery.
Results: Preoperative SE averaged −7.50 ± 1.16 D (ReLEx) and −7.32 ± 1.09 D (FS-LASIK). For all eyes, mean corrected distance visual acuity remained unchanged in both groups. For eyes with emmetropia as target refraction, 41% of ReLEx and 61% of FS-LASIK eyes had an uncorrected distance visual acuity of logMAR ≤ 0.10 at day 1 after surgery, increasing to, respectively, 88% and 69% at 3 months. Mean SE was −0.06 ± 0.35 D 3 months after ReLEx and −0.53 ± 0.60 D after FS-LASIK. The proportion of eyes within ±1.00 D after 3 months was 100% (ReLEx) and 85% (FS-LASIK). For a 6.0-mm pupil, corneal spherical aberrations increased significantly less in ReLEx than FS-LASIK eyes.
Conclusions: ReLEx is an all-in-one femtosecond laser refractive procedure, and in this study, results were comparable to FS-LASIK. Refractive predictability and corneal aberrations at 3 months seemed better than or equal to FS-LASIK, whereas visual recovery after ReLEx was slower.