This issue of Acta printed and electronic


  • Einar Stefánsson

The illustration on the cover shows surgical treatment of iris melanoma as reported by Klauber et al. in this issue of ACTA.

Review Article

Ernest et al in the Netherlands critically review validity and reproducibility of techniques used for assessing visual field progression in glaucoma.


Mehlsen et al in Aarhus propose that eye screening frequency in diabetic patients should be individualized based on risk assessment. They suggest that low risk diabetics may be screened more frequently than is necessary.

de Vries et al in the Netherlands suggest that glaucoma screening by opticians may be feasible but specificity is low.


Klauber et al in Copenhagen report good outome following resection of iris and irido-ciliary melanomas.

Bertelmann and Rieck in Berlin prefer surgical resection to cryotherapy for basal cell carcinoma.


Saarela et al in Finland found that the sensitivity and specificity of stereoscopic optic nerve head photographs and Heidelberg retina tomographs are influenced by the same factors.

Pemp et al in Vienna found that moxaverine, a phosphodiesterase inhibitor, increases choroidal and optic nerve blood flow.

Peeters et al in Maastricht suggest that timolol is more cost-effective than latanoprost in glaucoma treatment.


Muqit et al in UK and USA recommend the Pascal® laser system for treatment of vascular retinal disorders and find this similar to conventional treatment in clinical efficacy.

Kunikata et al in Japan found chemokines such as MIP-1β in the aqueous humor to be reduced following intraviteral injection of triamcinolone and this reflects improvement of macular edema in branch retinal vein occlusion following treatment.


Ang et al in Aberdeen found that anterior chamber depth increase slightly for the first 6 months following cataract surgery and remains stable thereafter. Best correced visual acuity remains stable.

Fong et al in Australia followed almost 1200 elderly cataract patients following surgery and found an average visual improvement of 2 lines.

Löfgren in Stockholm found that the cataractogenic effect of ultraviolet radiation is different in different types of rats.

Wang et al in China found bimanual and micro-coaxial phacoemulisfication to be similarly safe and effective procedures.


van Sorge et al in the Netherlands found a considerable risk of exposure keratopathy following silicone frontalis suspension in patients with blepharoptosis.

History of Ophthalmology

Grzybowski in Poland recalls Polish contributions in ophthalmolgoy.

Diagnosis/therapy in Ophthalmology

Ahnood and Toft in London and Copenhagen report orbital compartment syndrome with intraorbital air following a blow-out fracture.

Electronic Publications

The following publications are in the electronic part of the journal only and can be accessed at


El-Asrar et al in Saudi Arabia and Belgium suggest that the lysophosphatidic acid receptor pathway may be involved in inflammatory, angiogenic and fibrotic responses in proliferative vitreoretinal disorders.

Loughman et al in Ireland and South Africa tested two instruments for measuring macular pigment optical density and report different outcomes and substantial test – retest variability.

Koss et al in Germany found inflammatory markers and vascular endothelial growth factor to be higher in central compared to branch retinal vein occlusion.


Nanavaty et al in London found that posterior capsule opacification was similar with spheric and aspheric intraocular lenses.

Pediatric Ophthalmology

Horwood and Riddell in the UK examined the association between accommodation and vergence in exotropia.


Detry-Morel et al in Brussels found lower corneal hysteresis in Africans compared to Caucasians and suggest that this may contribute to glaucoma development in the African population.

Yoeruek et al in Germany suggest that decellularized porcine corneas may serve as scaffold for tissue engineering and cultivation of human corneal cells.


Agnifili et al in Italy used in vivo confocal microscopy to study the bulbar conjunctiva and found conjunctival microcysts in glaucoma patients treated with eye drops.

Wei et al in China examined the effect of the SPARC gene in trabecular meshwork.

Fuertes-Lazaro et al in Spain report that frequency doubling perimetry objectively corresponds to the anatomic distribution of retinal nervous tissue.

Letters to the Editor

Lee et al in UK and Sweden discuss the role of yellow intraocular lenses in the progression of age-related macular degeneration.

Chatziralli et al in Athens confirm the role of α1adrenergic blockers and suggest a role for benzodiazepines in intraoperative floppy iris syndrome.

Pärssinen in Finland warns of operating room mistakes with antibiotic concentrations.

Stilling-Vinther and Pedersen in Aarhus discuss side effects following anti-inflammatory treatment for posterior scleritis.

Alten et al in Germany report dacryoliths in the lacrimal gland ductile.

Tano et al in Japan used vitrectomy and bevacizumab for von Hippel-Lindau disease.

Hara et al in Japan describe cotton-wool spots and their fibre layer defects in interferon retinopathy.

Penha et al in Brazil, Venezuela, Costa Rica, Columbia and Puorto Rico report intravitreal bevacizumab and triamcinolone to be effective for diffuse macular oedema and the triamcinolone has longer action.

Sassa et al in Japan recommend infliximab for treatment of scleritis.

Davis et al in USA found no effect of beta blockers on age-related macular degeneration.

Ivastinovic et al in Austria implanted epiretinal prostheses in pig eyes with the help of dispase and vitrectomy.

Meyer et al in Bonn warn of variability in dosage of intravitreal injections.

Nangia et al in India and Germany found that undercorrection of refractive error is common in rural India and frequently impaires vision.

I hope the readers enjoy both the printed and electronic parts of the journal. The entire journal is available in the electronic form on If you want to comment on articles in the journal or add your own observations, feel free to submit a letter to the editor.