Osteoporosis in ankylosing spondylitis


: Dr. Debashish Danda, Department of Rheumatology and Clinical Immunology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India. Email: debashish.danda@cmcvellore.ac.in


Ankylosing spondylitis (AS) is a chronic inflammatory disorder, characterized by an inflammatory enthesopathy progressing to ossification and ankylosis. Osteoporosis is a well-reported complication of AS. Bone loss begins early in the disease at the spine, and later progresses to the hip. This reduction in bone density leads to an increased risk of fractures. However, there is a lack of awareness regarding this common complication, thus adding to the morbidity associated with AS. Early recognition, appropriate assessment and timely treatment of this complication will help reduce the attendant fracture risk due to decreased bone mass.