The Association between Severity of Atherosclerosis and Lower Urinary Tract Function in Male Patients with Lower Urinary Tract Symptoms
Version of Record online: 21 JUL 2011
© 2011 Blackwell Publishing Asia Pty Ltd
LUTS: Lower Urinary Tract Symptoms
Volume 4, Issue 1, pages 9–13, January 2012
How to Cite
TAKAHASHI, N., SHISHIDO, K., SATO, Y., OGAWA, S., OGURO, T., KATAOKA, M., SHIOMI, H., UCHIDA, H., HAGA, N., HOSOI, T., NOMIYA, M., AIKAWA, K., MURAKAMI, H. and YAMAGUCHI, O. (2012), The Association between Severity of Atherosclerosis and Lower Urinary Tract Function in Male Patients with Lower Urinary Tract Symptoms. LUTS: Lower Urinary Tract Symptoms, 4: 9–13. doi: 10.1111/j.1757-5672.2011.00098.x
- Issue online: 5 JAN 2012
- Version of Record online: 21 JUL 2011
- Received 30 January 2011; revised 14 May 2011; accepted 4 June 2011.
- lower urinary tract dysfunction;
- male lower urinary tract symptoms
Objectives: The present study was undertaken to investigate the association between the severity of atherosclerosis and lower urinary tract function in male patients with lower urinary tract symptoms.
Methods: Male patients with lower urinary tract symptoms were examined with routine investigation. The severity of atherosclerosis was assessed by ultrasound examination of carotid artery. Patients were divided into two groups: control group and atherosclerosis group. The voiding function and storage function were compared between the two groups.
Results: A total of 50 men (69.9 ± 9.1 years [mean ± standard deviation]) entered the study. There was no significant difference in age distribution (control group: 68.7 ± 7.6 years; atherosclerosis group: 72.5 ± 9.7 years) and prostate volume (control group: 26.5 ± 17.3 mL; atherosclerosis group: 22.2 ± 11.0 mL) between the two groups. In the voiding parameters, maximum flow rate in the atherosclerosis group (13.4 ± 5.5 mL/s, P < 0.05) was significantly lower than that in the control group (16.7 ± 7.7 mL/s). Postvoid residual urine volume showed no significant difference between the two groups. In the storage parameters, voided volume was significantly reduced in the atherosclerosis group (161.8 ± 46 mL, P < 0.05), as compared to control group (201.1 ± 78 mL). Moreover, daytime frequency was 7.13 ± 3.02 times in the control group, and significantly higher in the atherosclerosis group (8.75 ± 2.50 times, P < 0.05).
Conclusion: Development of atherosclerosis impairs both voiding and storage function independently of age, suggesting atherosclerosis leads to lower urinary dysfunction.