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Keywords:

  • happiness;
  • intervention;
  • mental health;
  • population;
  • review;
  • well-being

This review focuses on positive aspects of well-being, or flourishing. It examines evidence for the causes of positive well-being and also its consequences, including beneficial effects for many aspects of cognitive functioning, health, and social relationships. The neurobiological basis of psychological well-being is examined, and recent data on brain activation and neurochemical pathways are presented. Individuals vary widely in their habitual level of psychological well-being, and there is evidence for a seminal role of social factors and the early environment in this process. It is often assumed that the drivers of well-being are the same as (but in the opposite direction to) the drivers of ill-being, but while this is true for some drivers, others have more selective effects. Future developments in the science of well-being and its application require a fresh approach—beyond targeting the alleviation of disorder to a focus on personal and interpersonal flourishing. A universal intervention approach is outlined which may both increase population flourishing and reduce common mental health problems.