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Fig. S1.Pocillopora damicornis colonies un-inoculated (A) and inoculated (B) with V. harveyi in aquarium experiments and photographed after 2 days from the inoculum. (C) is a zooming on an infected colony at the end of the experiment and shows the multifocal and basal tissue loss, which moved fast to the apical portion of the colony. All images refer to the Experiment 2 (Table 2). Scale bars dimensions (approximately): (A) and (B) = 3 cm, (C) = 1 cm.

Fig. S2. Cultures on TCBS plates of un-inoculated (‘control’) and inoculated P. damicornis samples, showing the absence of growth and a high abundance of isolates (respectively). Biochemical (API galleries) and genetic (16S rDNA sequence analysis) assays confirmed that the bacterial isolates corresponded to the inoculated V. harveyi strain.

Fig. S3. SEM images displaying P. damicornis corals after experimental infection with Vibrio harveyi. (A) Necrotic coral tissue; (B) and (C) Zooming at different magnifications, revealing the lysing tissue (B) and a high number of bacterial cells adhering to the tissue surface (C).

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